Foam sclerotherapy vs. other forms of sclerotherapy and hemosiderin staining

Whenever I get foam sclerotherapy it results in staining that takes 1-1.5 years to fade. I recently had sclerotherapy treatment done that wasn't foam on the right side of my leg (plan is to do the left next week) to treat blue reticular veins - believed they were "feeding" my spider veins. My spider veins are light due to past laser treatments on them. I was told foam sclerotherapy is more likely to cause staining. From your experience, is this true? Also, what can I do to prevent the staining?

Answers from doctors (4)


Vanish Vein and Laser Center

Published on Jan 18, 2019

Foam sclerotherapy does not cause more staining than liquid sclerotherapy. There are many theories about why staining occurs, including the concentration of solution, leakage of the solution outside the vein, and even the patient's skin type. After more than 20 years of doing sclerotherapy, I have experienced staining and fortunately, it has not been often. Most times I could never explain why the staining occurred and neither could I predict who would stain. My recommendations are to use the lowest concentration necessary, inject slowly, and keep compression post-treatment for 48 hours.

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Answered by Vanish Vein and Laser Center

Foam sclerotherapy does not cause more staining than liquid sclerotherapy. There are many theories about why staining occurs, including the concentration of solution, leakage of the solution outside the vein, and even the patient's skin type. After more than 20 years of doing sclerotherapy, I have experienced staining and fortunately, it has not been often. Most times I could never explain why the staining occurred and neither could I predict who would stain. My recommendations are to use the lowest concentration necessary, inject slowly, and keep compression post-treatment for 48 hours.

Published on Jul 11, 2012


More About Doctor Laser Vein Center

Published on Nov 25, 2015

Staining or hyperpigmentation seems to be more the result of who is getting treated, not what the treatment is. In other words, certain patients tend to get staining after vein procedures in their legs. This seems to be related to the iron metabolism. People who have increased iron stores are more likely to stain. It is not known if there is anything that can be done.

Answered by Laser Vein Center (View Profile)

Staining or hyperpigmentation seems to be more the result of who is getting treated, not what the treatment is. In other words, certain patients tend to get staining after vein procedures in their legs. This seems to be related to the iron metabolism. People who have increased iron stores are more likely to stain. It is not known if there is anything that can be done.

Published on Jul 11, 2012


Vascular Center and Vein Clinic of Southern Indiana

Published on Nov 23, 2015

Sclerotherapy results are largely dependent on the ability to properly inject the vein, followed by compression.

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Answered by Vascular Center and Vein Clinic of Southern Indiana

Sclerotherapy results are largely dependent on the ability to properly inject the vein, followed by compression.

Published on Jul 11, 2012


West Coast Medicine and Cardiology

Published on Nov 23, 2015

You should be wearing stockings even after treatment, for 2 weeks at the very minimum. Also, the type of sclerosing agent varies--for example, STS vs. Poly and the dosing and concentration. Ask about choices as some skins do better with one over the other. Lastly, you should ask about liquid vs. foam for treatment choice for your reticular veins and perhaps, have small sections treated in staged therapies.

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Answered by West Coast Medicine and Cardiology

You should be wearing stockings even after treatment, for 2 weeks at the very minimum. Also, the type of sclerosing agent varies--for example, STS vs. Poly and the dosing and concentration. Ask about choices as some skins do better with one over the other. Lastly, you should ask about liquid vs. foam for treatment choice for your reticular veins and perhaps, have small sections treated in staged therapies.

Published on Jul 11, 2012


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